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- Jumping archer fish exhibit multiple modes of fin–fin interaction 21. November 2020Aquatic organisms jumping for aerial prey require high-performance propulsion, accurate aim, and trajectory control to succeed. Archer fish, capable of jumping up to twice their body length out of the water, address these considerations through multifaceted fin and body kinematics. In this study, we utilized 3D synthetic aperture particle image velocimetry to visualize the wakes […]Leah Mendelson and Alexandra H Techet
- The effect of variable stiffness of tuna-like fish body and fin on swimming performance 7. November 2020The work in this paper focuses on the examination of the effect of variable stiffness distributions on the kinematics and propulsion performance of a tuna-like swimmer. This is performed with the use of a recently developed fully coupled fluid-structure interaction solver. The two different scenarios considered in the present study are the stiffness varied along […]Yang Luo, Qing Xiao, Guangyu Shi, Guang Pan and Daoyi Chen
- Reconstructing full-field flapping wing dynamics from sparse measurements 7. November 2020Flapping insect wings deform during flight. This deformation benefits the insect’s aerodynamic force production as well as energetic efficiency. However, it is challenging to measure wing displacement field in flying insects. Many points must be tracked over the wing’s surface to resolve its instantaneous shape. To reduce the number of points one is required to […]William Johns, Lisa Davis and Mark Jankauski
- Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth 20. November 2020Neutralizing antibodies elicited by HIV-1 coevolve with viral envelope proteins (Env) in distinctive patterns, in some cases acquiring substantial breadth. We report that primary HIV-1 envelope proteins—when expressed by simian-human immunodeficiency viruses in rhesus macaques—elicited patterns of Env-antibody coevolution strikingly similar to those in humans. This included conserved immunogenetic, structural and chemical solutions to epitope […]Roark, R. S., Li, H., Williams, W. B., Chug, H., Mason, R. D., Gorman, J., Wang, S., Lee, F.-H., Rando, J., Bonsignori, M., Hwang, K.-K., Saunders, K. O., Wiehe, K., Moody, M. A., Hraber, P. T., Wagh, K., Giorgi, E. E., Russell, R. M., Bibollet-Ruche, F., Liu, W., Connell, J., Smith, A. G., DeVoto, J., Murphy, A. I., Smith, J., Ding, W., Zhao, C., Chohan, N., Okumura, M., Rosario, C., Ding, Y., Lindemuth, E., Bauer, A. M., Bar, K. J., Ambrozak, D., Chao, C. W., Chuang, G.-Y., Geng, H., Lin, B. C., Louder, M. K., Nguyen, R., Zhang, B., Lewis, M. G., Raymond, D., Doria-Rose, N. A., Schramm, C. A., Douek, D. C., Roederer, M., Kepler, T. B., Kelsoe, G., Mascola, J. R., Kwong, P. D., Korber, B. T., Harrison, S. C., Haynes, B. F., Hahn, B. H., Shaw, G. M.
- De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2 19. November 2020We developed a de novo protein design strategy to swiftly engineer decoys for neutralizing pathogens that exploit extracellular host proteins to infect the cell. Our pipeline allowed the design, validation, and optimization of de novo hACE2 decoys to neutralize SARS-CoV-2. The best decoy, CTC-445.2, binds with low nanomolar affinity and high specificity to the RBD […]Linsky, T. W., Vergara, R., Codina, N., Nelson, J. W., Walker, M. J., Su, W., Barnes, C. O., Hsiang, T.-Y., Esser-Nobis, K., Yu, K., Reneer, Z. B., Hou, Y. J., Priya, T., Mitsumoto, M., Pong, A., Lau, U. Y., Mason, M. L., Chen, J., Chen, A., Berrocal, T., Peng, H., Clairmont, N. S., Castellanos, J., Lin, Y.-R., Josephson-Day, A., Baric, R. S., Fuller, D. H., Walkey, C. D., Ross, T. M., Swanson, R., Bjorkman, P. J., Gale, M., Blancas-Mejia, L. M., Yen, H.-L., Silva, D.-A.
- How directed evolution reshapes the energy landscape in an enzyme to boost catalysis 19. November 2020The advent of biocatalysts designed computationally and optimized by laboratory evolution provides an opportunity to explore molecular strategies for augmenting catalytic function. Applying a suite of NMR, crystallographic, and stopped-flow techniques to an enzyme designed for an elementary proton transfer reaction, we show how directed evolution gradually altered the conformational ensemble of the protein scaffold […]Otten, R., Padua, R. A. P., Bunzel, H. A., Nguyen, V., Pitsawong, W., Patterson, M., Sui, S., Perry, S. L., Cohen, A. E., Hilvert, D., Kern, D.
- Publisher Correction: Large Chinese land carbon sink estimated from atmospheric carbon dioxide data 24. November 2020Nature, Published online: 24 November 2020; doi:10.1038/s41586-020-2986-1Publisher Correction: Large Chinese land carbon sink estimated from atmospheric carbon dioxide dataJing Wang
- Author Correction: Innovations present in the primate interneuron repertoire 24. November 2020Nature, Published online: 24 November 2020; doi:10.1038/s41586-020-2874-8Author Correction: Innovations present in the primate interneuron repertoireFenna M. Krienen
- Why emergency COVID-vaccine approvals pose a dilemma for scientists 23. November 2020Nature, Published online: 23 November 2020; doi:10.1038/d41586-020-03219-yImmunizations are speeding towards approval before clinical trials end, but scientists say this could complicate efforts to study long-term effects.David Cyranoski
- Synapse: Spark Biomimicry Ideas 26. August 2019Synapse by Biomimicry 3.8 is an environment for our staff to share their expertise and thought leadership in biomimicry with the world. It’s our way of inviting you to join us in our awe for the natural world and discover the inspirational ways that innovators from around the world are using biomimicry to solve tough challenges, […]jessica
- Beautiful News South Africa implements Biomimicry into Town Design 27. June 2018“For us to coexist with nature I think we really need to humble ourselves and learn from nature,” Swain says. As the founder of the NPO BioWise, she uses biomimicry to create sustainable solutions to environmental problems. To see the whole article and more, check out Beautiful News South Africa’s Facebook page. The post […]austin
- Impressive Impact: 2016-2018 Cohort Grads Ready to Lead 24. April 2018The newest set of Certified Biomimicry Professionals graduated during a ceremony in Kona, Hawaii The post Impressive Impact: 2016-2018 Cohort Grads Ready to Lead appeared first on Biomimicry 3.8.jenna